IlliniGuys Predictions - USC at Illinois

September 26, 2025

Last week did not go as planned as the Indiana Hoosiers took the Illini out to the woodshed and applied a beating.

Now the Illini face #21 USC.

How will this game turn out?

It's time to see what the guys think.

IlliniGuy Prediction 25 Season Record
IlliniGuy Larry USC 24-16 3-1
IlliniGuy Brad USC 38-28 3-1
IlliniGuy Mike Illinois 31-28 3-1
Kedric Prince USC 38-24 4-0
Matt Stevens USC30-16 4-0
Zain Bando USC 27-20 3-1
Connor Cagley USC 34-17 3-1
Steve Sturm USC 30-27 3-1
Patrick Quinn USC 31-28 3-1
IlliniGuy Chris USC 42-24 3-1
IlliniGuy Karl Illinois 21-20 3-1

Podcasts

Illini Defeat Purdue on the Road 43-27 - #509

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IlliniGuys Sports Spectacular - Illini FB Beats USC on to Purdue, BB & Game Predictions - 10.3.25 - S5E8

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I on the Illini - Illini FB Preview: Purdue #508

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I on the Illini LIVE/Illini Central Postgame - Redemption Win Over USC - #507

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Indiana Loss, USC Preview and Hoops Update S5Ep7 9.26.25

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Illini Football Preview - USC - #506

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Heat Checks & Hail Marys – 6 Days to ?

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Illini Nuked by Hoosiers 63-10 - #505

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Illini vs Indiana, 2025-26 Illini Hoops Schedule, Game Predictions & More - S5Ep6

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2025-26 Illini B1G Basketball Schedule - #504

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Illini Football Preview – Indiana Hoosiers #503

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Illini Crush Western Michigan - #502

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IlliniGuys Sports Spectacular - $100 Million Donation, Illini Football Update & Canelo vs Crawford S5Ep5 - 9.12.25

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Illinois Football Preview - Western Michigan - #501

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Illini Destroy Duke 45-19 #500

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