The Illini had an off-week after the 24-0 thrashing by the Wisconsin Badgers, but travel to Happy Valley to face No. 7 Penn State, which is favored by 24 points.
Let's see how the predictions turn out. It's time to see if anyone has a crystal ball that works when it comes to the IlliniGuys staff.
| IlliniGuy | Prediction | Season Record |
| Larry Smith | Penn State 34-13 | 4-3 |
| Brad Sturdy | Penn State 38-13 | 4-3 |
| Mike Cagley | Penn State 30-3 | 3-4 |
| Kedric Prince | Penn State 55-10 | 5-2 |
| Matt Stevens | Penn State 27-9 | 5-2 |
| Brandon Wildman | Penn State 31-10 | 5-2 |
| Connor Cagley | Penn State 34-6 | 5-2 |
| Steve Sturm | Penn State 35-10 | 6-1 |
| Patrick Quinn | Penn State 14-3 | 4-3 |
| Kirkland Chappell | Penn State 41-17 | 3-4 |
| Shannon Denny | Penn State 32-12 | 6-1 |
| IlliniGuy Chris | Penn State 42-6 | 4-3 |
| IlliniGuy Karl | Penn State 48-3 | 3-4 |
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